What type of cancer produces hCG?
HCG can be elevated in a number of other malignancies, including cancers of the liver, lung, pancreas and stomach. In germ cell tumors of the testis, including both seminomas and NSGCT, cancerous cells can transform into syncytiotrophoblasts (a normal component of the placenta) and secrete HCG.
Can a positive pregnancy test indicate cancer?
Testing for HCG (human chorionic gonadotropin) in the urine is indicated when there is a suspicion of certain cancers. HCG is normally produced by the placenta and forms the basis for the most widely used pregnancy test. But it can also be a “marker” for certain cancers.
Can ovarian cancer cause elevated hCG levels?
An increased level of hCG may also sometimes be seen in a woman who has an early stage germ cell ovarian cancer, so there is a chance that if someone with this type of cancer does a pregnancy test, a positive result will be produced.
What causes high hCG levels if not pregnant?
An elevated β-hCG in the absence of viable pregnancy can occur for multiple reasons and has a broad differential diagnosis including miscarriage, ectopic pregnancy, pituitary hCG production, trophoblastic disease and phantom hCG.
What level of hCG indicates cancer?
Generally speaking, any level above normal may indicate cancer. Often it’s not hard to tell, since hCG levels can skyrocket to 300-10,000 mIU/mL in some types of cancer [3, 4]. If your hCG or β-hCG levels are high, your doctor may pursue more aggressive or longer treatment options [3, 4].
What cancer causes false positive pregnancy test?
cancers of the ovary, bladder, kidney, liver, lung, colon, breast, and stomach. phantom hCG, where antibodies interfere with the testing kit. ovarian cysts that produce hCG. kidney disease or urinary tract infections.
What kind of cancer mimics pregnancy?
Choriocarcinoma is a rare cancer that occurs as an abnormal pregnancy. A baby may or may not develop in this type of pregnancy. The cancer may also occur after a normal pregnancy. But it most often occurs with a complete hydatidiform mole.
Would an ultrasound show ovarian cancer?
Ultrasound is often the first test done if a problem with the ovaries is suspected. It can be used to find an ovarian tumor and to check if it is a solid mass (tumor) or a fluid-filled cyst. It can also be used to get a better look at the ovary to see how big it is and how it looks inside.
Why would hCG levels be high?
If you are pregnant, very high levels of hCG can mean a multiple pregnancy (such as twins or triplets). It can also mean a molar pregnancy or Down syndrome. You may also be further along in an early pregnancy than you thought, based on your last menstrual period.
What causes elevated hCG levels?
At a Glance. Although the most common cause of an elevated HCG level in females is pregnancy, occasionally, a HCG-secreting tumor is suspected and other conditions such as gestational trophoblastic disease (GTD), nontrophoblastic neoplasms, or a pituitary source of HCG, must be considered.