Can a Spitz nevus turn into melanoma?

Can a Spitz nevus turn cancerous?

A Spitz nevus is a rare type of skin mole that usually affects young people and children. Although it can look like a serious form of skin cancer called melanoma, a Spitz nevus lesion isn’t considered cancerous.

Is Spitzoid melanoma aggressive?

Although there is a paucity of data, several smaller studies have suggested spitzoid melanomas are less aggressive and have a lower mortality rate when compared with conventional malignant melanoma, he said.

Is a Spitz nevus bad?

There is debate as to whether the PSCNOR is an entity in its own right or whether it is a variation of a Spitz naevus. Although both lesions are benign, they can have similar clinical and histopathological features to melanoma, making their assessment difficult and best left in the hands of a specialist.

What is an atypical Spitz nevus?

Atypical Spitz nevi are described as conventional Spitz nevi with 1 or more atypical features with indeterminate biological potential. Features of atypical Spitz include larger size (>6 mm), irregular borders, irregular topography, or ulceration.

What does Spitzoid melanoma look like?

Spitzoid melanoma presents as a changing and enlarging papule or nodule. It can be amelanotic (nonpigmented, red) or pigmented (brown, black or blue). Advanced Spitzoid melanoma may be crusted and ulcerated. It is most often located on the head or extremities.

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Is Spitzoid melanoma genetic?

Based on the observation that a considerable portion of spitzoid melanomas have the genetic hallmarks of other types of cutaneous melanomas, the 2018 WHO classification of skin tumors introduced the concept of Spitz melanoma (malignant Spitz tumor) as a melanoma subtype that not only has the morphologic features of …

What type of melanoma is Spitzoid?

Spitzoid melanoma is a subtype of melanoma that, clinically and histologically, resembles a Spitz nevus. Clinically, spitzoid melanomas usually evolve from amelanotic nodular lesions, growing to 1 cm or more in diameter.

How quickly does a malignant melanoma spread?

Melanoma can grow very quickly. It can become life-threatening in as little as six weeks and, if untreated, it can spread to other parts of the body. Melanoma can appear on skin not normally exposed to the sun. Nodular melanoma is a highly dangerous form of melanoma that looks different from common melanomas.

How often is Spitz nevus misdiagnosed?

Even if the biopsies are sometimes performed, owing to the overlap histopathologic features between melanoma and benign nevus, misdiagnosis is often. One study showed that up to 40% of children originally diagnosed with Spitz nevi were later found to have melanomas [5].

What is a Spitz nevus?

Spitz nevus (Epithelioid and Spindle-Cell Nevus) is an uncommon, benign, melanocytic nevus that is usually acquired and has histologic features that overlap with those of melanoma.

Can melanoma have no pigment?

For example, certain melanomas may have no color at all. Physicians refer to these as “amelanotic” melanomas, because they are conspicuously missing melanin, the dark pigment that gives most moles and melanomas their color.

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