What kind of cancer does hydrochlorothiazide cause?
[8/20/2020] The U.S. Food and Drug Administration has approved changes to the hydrochlorothiazide (HCTZ) drug label to inform health care professionals and patients about a small increased risk of non-melanoma skin cancer (basal cell skin cancer or squamous cell skin cancer) associated with HCTZ use and to encourage …
Hydrochlorothiazide is photosensitizing and has been linked to lip cancer. We found a dose-dependent increased risk of nonmelanoma skin cancer, particularly squamous cell carcinoma, among users of hydrochlorothiazide.
Can diuretics cause cancer?
The use of thiazide diuretics was associated with an increased risk of squamous cell carcinoma (adjusted odds ratio (aOR), 1.86; 95% confidence interval (CI), 1.23 – 2.80) and marginally increased risk of basal cell carcinoma (aOR, 1.19; 95% CI, 1.02 – 1.38) and malignant melanoma (aOR, 1.14; 95% CI, 1.01 – 1.29).
Can hydrochlorothiazide cause kidney damage?
Popular diuretics include hydrochlorothiazide, furosemide, and spironolactone. They are associated with a risk for acute kidney injury.
What can you take instead of hydrochlorothiazide?
Hydrochlorothiazide (HCTZ) is one of the most commonly prescribed generic medications to lower blood pressure and protect people from these issues, but it turns out there’s an alternative that might be more effective—chlorthalidone.
What are the long term effects of taking hydrochlorothiazide?
If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks.
Is it safe to take hydrochlorothiazide long term?
Take as directed
Hydrochlorothiazide is used for long-term treatment. It comes with serious risks if you don’t take it as prescribed. If you stop taking the drug or don’t take it at all: Your swelling and high blood pressure might get worse. High blood pressure raises your risk of heart attack or stroke.
Is there a black box warning for hydrochlorothiazide?
A black box warning is attached to hydrochlorothiazide due to its ability to cause fetal mortality in women using the drug to treat high blood pressure.
Why should I stay out of the sun when taking hydrochlorothiazide?
Hydrochlorothiazide is a prescription drug used to treat high blood pressure and swelling. It is known to make skin more sensitive to ultraviolet radiation and sunlight, meaning patients can get sunburned more easily.
Which blood pressure medication causes skin cancer?
In studies, only the blood pressure medications that contain hydrochlorothiazide have been linked to an increased risk of skin cancer. Researchers speculate this happens because hydrochlorothiazide makes the skin more sensitive to the sun.
Do diuretics make you poop?
Because diuretics make you urinate more often, these drugs can cause constipation. Remedies for heartburn and indigestion often contain aluminum, which can slow down your system and cause constipation.
What is hydrochlorothiazide used for?
Hydrochlorothiazide is used to treat edema (fluid retention; excess fluid held in body tissues) caused by various medical problems, including heart, kidney, and liver disease and to treat edema caused by using certain medications including estrogen and corticosteroids.