Can hydrochlorothiazide cause melanoma?

What kind of cancer does hydrochlorothiazide cause?

[8/20/2020] The U.S. Food and Drug Administration has approved changes to the hydrochlorothiazide (HCTZ) drug label to inform health care professionals and patients about a small increased risk of non-melanoma skin cancer (basal cell skin cancer or squamous cell skin cancer) associated with HCTZ use and to encourage …

Can hydrochlorothiazide cause skin cancer?

The antihypertensive agent hydrochlorothiazide (HCTZ) was recently found to be strongly associated with increased risks of squamous cell carcinoma (SCC) of the lip,1,2 non-lip SCC of the skin3 and more rare forms of non-melanoma skin cancer (NMSC).

Can water pills cause cancer?

Conclusions. Our results suggested that the use of thiazide diuretics may be associated with an increased risk of skin cancers. This association was most prominent between the use of hydrochlorothiazide or hydrochlorothiazide combination medications and the risk of squamous cell carcinoma.

What drugs cause melanoma?

Interestingly, one of the most widely used drugs, i.e. the antihypertensive drugs and acetylsalicylic acid, are pointed out as probably triggering the development of melanoma.

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What are the long term effects of taking hydrochlorothiazide?

If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks.

Can I eat bananas while taking hydrochlorothiazide?

Because Dyazide (triamterene / hydrochlorothiazide) can increase your body’s potassium levels, you might have to be careful when eating foods high in potassium (bananas, avocados, black beans). If you eat bananas or other high potassium foods on a regular basis, you can usually continue to eat them.

Can you just stop taking hydrochlorothiazide?

Do not stop using hydrochlorothiazide and metoprolol suddenly, even if you feel fine. Stopping suddenly may cause serious or life-threatening heart problems. Follow your doctor’s instructions about tapering your dose. Store at room temperature away from moisture and heat.

Does hydrochlorothiazide 25 mg cause cancer?

Hydrochlorothiazide is photosensitizing and has been linked to lip cancer. We found a dose-dependent increased risk of nonmelanoma skin cancer, particularly squamous cell carcinoma, among users of hydrochlorothiazide.

Does hydrochlorothiazide have a black box warning?

A black box warning is attached to hydrochlorothiazide due to its ability to cause fetal mortality in women using the drug to treat high blood pressure.

Is there an alternative to hydrochlorothiazide?

Chlorthalidone is often offered as an alternative to HCTZ, but has limited pharmaceutical formulations.

Is there a recall on hydrochlorothiazide 12.5 mg?

Although neither amlodipine nor hydrochlorothiazide are currently under recall on their own, they are when combined with some other medications.

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What are the side effects from hydrochlorothiazide?

The more common side effects that can occur with hydrochlorothiazide include:

  • blood pressure that’s lower than normal (especially when standing up after sitting or lying down)
  • dizziness.
  • headache.
  • weakness.
  • erectile dysfunction (trouble getting or keeping an erection)
  • tingling in your hands, legs, and feet.

How do you know if melanoma has spread?

Some — but not all — patients need testing. Testing can help your dermatologist discover whether the melanoma has spread beyond the skin. Medical tests that you may need include blood work and imaging tests like an MRI scan, CAT scan, or x-ray.

Is there a pill for melanoma?

Dabrafenib (Tafinlar), encorafenib (Braftovi), and vemurafenib (Zelboraf) are FDA-approved targeted therapies for people with both unresectable stage III and stage IV melanoma. These drugs, taken as a pill, are specifically used when the melanoma tumors have a V600E or V600K mutation in the BRAF gene (see Diagnosis).

What stage of melanoma has the best prognosis?

Five-Year Survival Rate by Melanoma Stage:

  • Localized melanoma: Stage 0, Stage I, and Stage II: 98.4%
  • Regional melanoma: Stage III: 63.6%
  • Metastatic melanoma: Stage IV: 22.5%