Frequent question: What type of cancer does CA 125 test for?

Does CA125 detect all cancers?

Blood test (CA125 test)

CA125 is produced by some ovarian cancer cells. A high level of CA125 in your blood could be a sign of ovarian cancer. But a raised CA125 level does not mean you definitely have cancer, as it can also be caused by other conditions such as endometriosis, fibroids and even pregnancy.

What cancer marker is a associated with CA125?

Cancer antigen 125 (CA 125) is the only tumor marker recommended for clinical use in the diagnosis and management of ovarian cancer. The reference range of CA 125 is 0-35 units/mL (0-35 kU/L).

Is CA125 elevated in colon cancer?

Irritation of these foci in certain reactive or neoplastic lesions causes the serum CA125 concentration to increase. CA125 can also be detected in the tissue of gastrointestinal cancers, including stomach and colon cancer. Previous reports have shown that CA125 is a sensitive marker of PD of gastric cancer.

Can CA125 detect stomach cancer?

CA125 is originally found as a specific biological marker for ovarian cancer, and is considered to be a method of diagnosing gastric cancer. It is more frequently positive with peritoneal recurrence, and the importance of CA125 in the evaluation of peritoneal metastasis is suggested.

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What is a bad CA 125 level?

In the patient who is being evaluated for a pelvic mass, a CA 125 level greater than 65 is associated with malignancy in approximately 90% of cases. However, without an obvious pelvic mass, this association is much weaker.

What happens if my CA 125 is high?

Results. Results of the CA 125 test are measured in units per milliliter (U/mL). The normal value is less than 46 U/mL. If your CA 125 level is higher than normal, you may have a benign condition, or the test result could mean that you have ovarian, endometrial, peritoneal or fallopian tube cancer.

Can you be fully cured of ovarian cancer?

Around two in ten women with advanced-stage ovarian cancer are effectively cured and survive at least 12 years after the treatment as per the research. Your response to cancer therapy and chances for a cure depend on the type and the staging of ovarian cancer at the time of diagnosis.

How accurate is the CA 125 blood test?

Results: Using a CA125 cutoff of 30 U/mL, an overall sensitivity of 94.8% (96.6% specificity) was obtained when comparing malignancies versus healthy postmenopausal controls, whereas a cutoff of 65 U/mL provided a sensitivity of 83.9% (99.6% specificity).

Can stress cause CA125 to rise?

The most popular current theories suggest that CA 125 is synthesized by mesothelial cells in response to stress, which can be either mechanical stress caused by fluid overload, or inflammatory stress instigated by the release of mediators such as TNFα and interleukins [5,6].

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How high can CA-125 levels go?

Eventually, a CA 125 level of 35 units was found to be a useful cutoff point, with 99% of healthy women having values less than 35. Levels above 35 units are certainly seen in healthy women, but beyond the cutoff point of 35, the higher the value, the more likely there is trouble somewhere in the body.

How can I lower my CA-125 naturally?

However, there are some lifestyle factors you can control to decrease your risk of ovarian cancer.

  1. Exercise and Diet. By maintaining a weekly exercise regime and a healthy diet, the risk of ovarian cancer decreases. …
  2. Oral Contraceptives. …
  3. Avoiding Carcinogens. …
  4. Pregnancy & Breastfeeding. …
  5. Healthy Lifestyle.

Can cancer marker detect colon cancer?

The most common tumor marker for colorectal cancer is carcinoembryonic antigen (CEA). Blood tests for this tumor marker can sometimes suggest someone might have colorectal cancer, but they can’t be used alone to screen for or diagnose cancer.