How bad is cisplatin?
Cisplatin may cause serious kidney problems. Tell you doctor right away if you have blood in urine, change in frequency of urination or amount of urine, difficulty in breathing, drowsiness, increased thirst, loss of appetite, nausea or vomiting, swelling of the feet or lower legs, or weakness.
What type of chemo is cisplatin?
Cisplatin is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. This medication is classified as an “alkylating agent.” (For more detail, see “How Cisplatin Works” section below).
What are the long term effects of cisplatin?
Cisplatin (CDDP) is a frequently employed chemotherapeutic drug both in curative and palliative settings. When cancer patients are cured due to CDDP therapy, they unfortunately often experience severe long‐term side effects including irreversible hearing loss (ototoxicity) and permanent neuronal and renal damage.
Will I lose my hair on cisplatin?
v Hair loss is minimal with cisplatin, but some patients do experience more hair loss than others. Hair growth should return upon completion of treatment. v Nausea and vomiting are not unusual but are less common today than in the past because of much improved anti-nausea medications.
How long does cisplatin stay in the body?
The first elimination half-life (t1/2) for cisplatin was 5.02 months and the second 37.0 months. For oxaliplatin, these half-lifes were 1.37 and 535 months.
What is the most powerful chemotherapy?
Doxorubicin (Adriamycin) is one of the most powerful chemotherapy drugs ever invented. It can kill cancer cells at every point in their life cycle, and it’s used to treat a wide variety of cancers. Unfortunately, the drug can also damage heart cells, so a patient can’t take it indefinitely.
What are the side effects of cisplatin chemotherapy?
Common side effects of cisplatin
- Risk of infection. This treatment can reduce the number of white blood cells in your blood. …
- Bruising and bleeding. …
- Anaemia (low number of red blood cells) …
- Feeling sick. …
- Loss of appetite. …
- Changes to your taste. …
- Effects on the kidneys. …
- Changes in hearing.
How many cycles of cisplatin can you have?
You usually have between 4 to 6 cycles of treatment taking from 3 to 6 months. You have gemcitabine as a drip into your bloodstream over 30 minutes. You have cisplatin as a drip into your bloodstream over 1 to 4 hours.
When do cisplatin side effects start?
Nausea and vomiting usually begin within 1 to 4 hours after treatment and last up to 24 hours. Various degrees of vomiting, nausea and/or anorexia may persist for up to 1 week after treatment.
How much cisplatin can you have?
As a single agent, cisplatin (cisplatin injection) should be administered at a dose of 100 mg/m2 IV per cycle once every four weeks.
How many cycles of gemcitabine and cisplatin can you have?
Gemcitabine + cisplatin is repeated every 21 or 28 days. This is known as one Cycle. Each cycle may be repeated up to four times if the disease is not metastatic. If the disease is metastatic, then each cycle may be repeated up to 6 times.