Is germ cell tumor dangerous?

Is germ cell tumors deadly?

Like tumors that form in other places in the body, germ cell tumors can be benign (not cancerous) or malignant (cancerous). The most common types of germ cell tumors include: Teratomas. These tumors are benign, but can become malignant.

What is the survival rate of germ cell tumor?

The survival and cure rates also depend on several factors, including the stage of the disease. The cure rate for children with a stage I or stage II germ cell tumor is 90%. The cure rate for a stage III tumor is 87%. The cure rate for a stage IV tumor is 82%.

Is germ cell tumors curable?

Germ cell tumors tend to respond to treatment and many can be cured, even when diagnosed at a late stage.

How aggressive is germ cell cancer?

It’s often an aggressive cancer that spreads quickly to the lymph nodes and other parts of the body. They’re typically treated with surgery and chemotherapy.

Do germ cell tumors come back?

How do providers treat benign (noncancerous) ovarian germ cell tumors? Healthcare providers remove benign tumors surgically. Sometimes, they need to remove the ovary (or part of the ovary) when removing the tumor. Benign tumors rarely grow back after providers remove them.

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Do germ cell tumors grow fast?

This is a germ cell tumor that is most often malignant, but may also be benign. This tumor most often affects the ovaries or testes, and the lower spine. They are often malignant and grow fast.

How common is germ cell tumors?

Germ cell tumors are rare. Germ cell tumors account for about 2 to 4 percent of all cancers in children and adolescents younger than age 20. Germ cell tumors can spread (metastasize) to other parts of the body. The most common sites for metastasis are the lungs, liver, lymph nodes, and central nervous system.

Do germ cell tumors run in families?

Familial testicular germ cell tumors are well known in literature. Only few cases are reported where both brother and sister of the same family suffered from germ cell malignancies.

Where do germ cell tumors come from?

Germ cell tumors arise in the ovaries (in girls), the testes (in boys), and in several other locations, including the lower back (common in infancy), the abdomen, the chest, and within the brain. Germ cell tumors starting within the brain are discussed further under Brain Tumors.

How is germ cell tumors diagnosed?

A biopsy is the removal of a small amount of tissue for examination under a microscope. Other tests can suggest that a germ cell tumor is present, but only a biopsy can make a definite diagnosis and determine if the tumor is benign or cancerous. A pathologist then analyzes the sample(s).

What are the two types of germ cell tumors?

There are two types of germ cell tumors that start in the gonads, or reproductive organs: seminomas, which are slower-growing, and nonseminomas, which are faster-growing tumors. These germ cell tumors typically form during puberty.

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What is the most aggressive testicular tumor?

Embryonal carcinoma: present in about 40 percent of tumors and among the most rapidly growing and potentially aggressive tumor types. Embryonal carcinoma can secrete HCG or alpha fetoprotein (AFP). Yolk sac carcinoma: the most common type of tumor in children; responds well to chemotherapy in children and adults.