Is HCC an aggressive cancer?


How long can you live with hepatocellular carcinoma?

Average follow-up for all HCC patients in this study was 20.4 months. Overall median survival of all 389 patients was 11 months from the date of diagnosis. The 1-year survival rate was 49%, after 3 years 19% of all patients were still alive (Figure 2).

Is HCC a terminal for cancer?

Definition of terminal Hepatocellular Carcinoma

Among HCC patients, 15–20% present with end stage or terminal stage HCC. Their median survival is less than 3–4 months.

What type of cancer is HCC?

Primary liver cancer—cancer that starts in the liver—is called hepatocellular carcinoma (HCC). It is the sixth most-common form of cancer worldwide, but the third leading cause of death from cancer. HCC almost always occurs in people who have had liver disease for many years.

What is the survival rate for hepatocellular carcinoma?

Unfortunately, HCC is typically diagnosed late in its course, with a median survival following diagnosis of approximately 6 to 20 months. In the United States, 2 years survival is less than 50% and 5-year survival is only 10%.

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How long can you live with Stage 4 HCC?

Patients who have stage 1, localized, liver cancer have a 5-year survival rate of 33%. Those with regional, or stage 2 or 3 liver cancer, have an 11% 5-year survival rate. Patients with advanced, or stage 4 liver cancer have a 2% 5-year survival rate.

How fast do HCC tumors grow?

Question 5: how fast do tumors grow? The mean volume doubling time of small (,5 cm) HCCs ranges from 112 to 204 days; the interindividual variability of tumor growth is also very high, the individual doubling time ranging from 30 to 600 days (34–38).

How bad is HCC?

Overview. Hepatocellular carcinoma (HCC) is a type of liver cancer that begins in the hepatocytes, the main type of liver cell. While it’s considered a rare disease in the United States, HCC is responsible for around one million deaths worldwide every year.

Where does HCC metastasis to?

Tabulation of all extrahepatic metastatic sites showed the most common to be the lung in 81 (55%) patients, the abdominal lymph nodes in 60 (41%) patients, and the bone in 41 (28%) patients. Conclusion: The lung, abdominal lymph nodes, and bone are the most common sites of extrahepatic metastatic HCC.

What is the best treatment for HCC liver cancer?

Orthotopic liver transplantation (OLT) is an effective treatment for both HCC and underlying cirrhosis, and is considered the best therapeutic option.

Is hepatocellular carcinoma a fast growing cancer?

Liver cancer can spread quickly depending on the type of cancer. Hemangiosarcoma and angiosarcoma types of liver cancer are fast spreading, whereas hepatocellular carcinoma spreads late in the disease.

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What are the stages of HCC?

Histologic grade (G)

Stage Performance Status Tumor Stage
A4 3 tumors, < 3 cm
Stage B: Intermediate HCC Large, multinodular
Stage C: Advanced HCC 1-2 Vascular invasion or extrahepatic spread
Stage D: End-Stage HCC 3-4 Any

How does HCC spread?

Conclusion. HCC is an aggressive malignancy, and accurate staging is required for optimal treatment planning. Metastatic spread is by direct invasion, through ascites or via hematogenous or lymphatic routes.