What is platinum chemotherapy?
Platinum-based antineoplastic drugs (informally called platins) are chemotherapeutic agents used to treat cancer. They are coordination complexes of platinum. These drugs are used to treat almost half of people receiving chemotherapy for cancer.
Which chemo drugs are platinum-based?
The platinum-based drugs cisplatin, carboplatin and oxaliplatin are regularly prescribed in the treatment of cancer and while they are effective, their use is limited by their severe, dose-limiting side effects (also referred to as adverse effects/events).
What kind of chemo is Taxol?
Taxol is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. Taxol is classified as a “plant alkaloid,” a “taxane” and an “antimicrotubule agent.” (For more detail, see “How Taxol Works” section below).
What is the most powerful chemotherapy?
Doxorubicin (Adriamycin) is one of the most powerful chemotherapy drugs ever invented. It can kill cancer cells at every point in their life cycle, and it’s used to treat a wide variety of cancers. Unfortunately, the drug can also damage heart cells, so a patient can’t take it indefinitely.
Is there platinum in chemotherapy?
Platinum-based agents are important drugs or drug candidates for cancer chemotherapy. Traditional platinum drugs including the globally approved cisplatin, carboplatin and oxaliplatin are neutral platinum (II) complexes with two amine ligands and two additional ligands that can be aquated for further binding with DNA.
What does Taxol do to your body?
Taxol (paclitaxel) is a cancer chemotherapy medication that interferes with the growth of cancer cells and slows their growth and spread in the body and is used to treat breast cancer, lung cancer, and ovarian cancer. Taxol is also used to treat AIDS-related Kaposi’s sarcoma.
What are the side effects of Taxol chemotherapy?
The following Taxol side effects are common (occurring in greater than 30%) for patients taking Taxol:
- Low blood counts. …
- Hair loss.
- Arthralgias and myalgias, pain in the joints and muscles. …
- Peripheral neuropathy (numbness and tingling of the hands and feet)
- Nausea and vomiting (usually mild)
- Mouth sores.
How long does Taxol stay in your body?
The chemotherapy itself stays in the body within 2 -3 days of treatment but there are short-term and long-term side effects that patients may experience. Not all patients will experience all side effects but many will experience at least a few.
How does platinum chemo work?
Platinum-based drugs are effective against cancer because at their centre is a platinum atom joined to two ammonion molecules and two chloride ions. The compound is negatively charged, but when it enters the cancer cell it becomes positively charged because the chloride ions are replaced by water molecules.
Does platinum chemo cause hair loss?
Taste changes, metallic taste. Increases in blood tests measuring liver function. These return to normal once treatment is discontinued (see liver problems). Hair loss may cause hair loss; however, this side effect is uncommon.
Why is platinum in chemotherapy?
The platinum compounds are largely used in the treatment of lung, breast, ovarian, and colon cancers. The chemotherapeutic mechanism of platinum compounds is typical of DNA-binding alkylating agents. If the DNA damage exceeds the ability of the cell to repair, the cell undergoes apoptotic cell death.