Quick Answer: What genes are tested for breast cancer?

What genes are associated with breast cancer?

BRCA1 and BRCA2: The most common cause of hereditary breast cancer is an inherited mutation in the BRCA1 or BRCA2 gene. In normal cells, these genes help make proteins that repair damaged DNA.

What genetic testing is done for breast cancer?

The BRCA gene test is a blood test that’s done to determine if you have changes (mutations) in your DNA that increase the risk of breast cancer. Mutations in either breast cancer gene — BRCA1 or BRCA2 — significantly increase the risk of: Breast cancer.

Is genetic testing for breast cancer worth it?

Women who are carriers of mutated BRCA genes are known to have a significantly higher risk for developing breast and ovarian cancers than those who don’t.

Can breast cancer be passed down from paternal grandmother?

You are substantially more likely to have a genetic mutation linked to breast cancer if: You have blood relatives (grandmothers, mother, sisters, aunts) on either your mother’s or father’s side of the family who had breast cancer diagnosed before age 50.

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How can you prevent breast cancer if you have the gene?

For women with BRCA1 or BRCA2 genetic mutations, which substantially increase the risk of breast cancer, preventive removal of the breasts may be considered. This procedure is called a prophylactic mastectomy. It appears to reduce the risk of developing breast cancer by at least 90% to 95%.

What is the best way to diagnose breast cancer?

A biopsy is the only definitive way to make a diagnosis of breast cancer. During a biopsy, your doctor uses a specialized needle device guided by X-ray or another imaging test to extract a core of tissue from the suspicious area.

How long does genetic testing for breast cancer take?

Counselors can administer the test and properly interpret the results when they’re in — they take about three weeks. Genetic tests can be done in a primary-care doctor’s office.

Does insurance pay for breast cancer gene test?

Most insurance companies will cover the cost of genetic testing if you meet the conditions for testing. Finding out that you have a BRCA gene change should not affect your ability to get a job or get health insurance.

What are the disadvantages of genetic testing?

Some disadvantages, or risks, that come from genetic testing can include:

  • Testing may increase your stress and anxiety.
  • Results in some cases may return inconclusive or uncertain.
  • Negative impact on family and personal relationships.
  • You might not be eligible if you do not fit certain criteria required for testing.

How much does the breast cancer gene test cost?

The cost of testing ranges from approximately $300 to $5,000, depending on whether you are being tested for only a specific area(s) of a gene known to be abnormal or if hundreds of areas are being examined within multiple genes.

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Is hereditary breast cancer curable?

Survival rates after two years were 97 percent for women with a BRCA mutation and 96.6 percent for those without the mutation, the findings showed. After five years, survival rates were 83.8 percent and 85 percent, respectively. After 10 years, those rates were 73.4 percent and 70.1 percent, respectively.