What does N2 mean in lung cancer?


What is N2 lung cancer?

Simply defined, N2 disease in non–small cell lung cancer (NSCLC) is the presence of ipsilateral mediastinal nodal metastases. This definition does little justice to what is in actuality a heterogeneous and challenging patient population.

What does N2 disease mean?

The true prevalence of mediastinal lymph node metastases (N2 disease) in resected pathologic T1 (pT1) NSCLC must be known to define the role of invasive mediastinal staging in these patients.

What is N2 in cancer staging?

N2: The cancer has spread to 4 to 9 axillary lymph nodes. Or, it has spread to the internal mammary lymph nodes, but not the axillary lymph nodes. N3: The cancer has spread to 10 or more axillary lymph nodes, or it has spread to the lymph nodes located under the clavicle, or collarbone.

What does T3 N2 M0 mean?

M with a number 1 indicates that the cancer has spread beyond the original location in the body. Using an example from the National Cancer Institute, Breast Cancer staged as T3N2M0 would describe a large (T3) tumor that has spread to the nearby lymph nodes (N2) but has not spread to other parts of the body (M0).

What is the survival rate of stage 3 cancer?

According to the American Cancer Society data derived from a database of people diagnosed with lung cancer between 1999 and 2010, the five-year survival rate for stage 3A NSCLC is about 36 percent. For stage 3B cancers the survival rate is about 26 percent. For stage 3C cancers the survival rate is about 1 percent.

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What’s the worst cancer?

List of cancer mortality rates in the United States

Type Age Adjusted Mortality Rates (per 100,000 people) during 2013-2017
Colorectal cancer 13.9
Liver cancer and bile duct cancer 6.6
Gallbladder cancer 0.6
Pancreatic cancer 11.0