What is treatment for desmoplastic melanoma?

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Is desmoplastic melanoma curable?

Desmoplastic melanoma is highly curable when diagnosed early.

How aggressive is desmoplastic melanoma?

The locally aggressive nature of DM is a common theme in the literature. In our series, the lesions had a mean Breslow thickness of 5.09 mm and a 21% incidence of local recurrence. The incidence of local recurrence for DM reported in the literature has ranged from 11% to 40%.

Can desmoplastic melanoma spread?

Desmoplastic melanoma has a propensity for neurotropism, frequently associated with nerve invasion, and spread along fascial planes.

Is desmoplastic melanoma slow growing?

Clinically, desmoplastic malignant melanoma usually develops in the elderly on sun exposed skin and commonly presents as a slow growing infiltrated non-specific plaque or nodule that may be amelanotic in up to 50% of lesions.

What does lentigo melanoma look like?

The visual symptoms of lentigo maligna melanoma are very similar to those of lentigo maligna. Both look like a flat or slightly raised brown patch, similar to a freckle or age spot. They have a smooth surface and an irregular shape. While they’re usually a shade of brown, they can also be pink, red, or white.

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How serious is desmoplastic melanoma?

A study of 1129 desmoplastic melanoma patients in the United States (1992–2007) reported a 5-year specific survival rate of 85% and 10-year survival of 80%.

How long can you have superficial spreading melanoma?

According to a recently published study looking at nearly 100,000 people with superficial spreading melanoma, the overall five-year survival rate was 95 percent and rising. That means that 95 percent of people with superficial spreading melanoma were alive five years after being diagnosed.

What is Spitzoid melanoma?

Spitzoid melanoma is a type of skin cancer. It begins when the melanocytes in the skin grow out of control and form tumors. Melanocytes are the cells responsible for making melanin, the pigment that determines the color of the skin.

How common is melanoma in the eye?

Ocular melanoma is the most common primary cancer affecting the eye. However, it is a rare disorder and is estimated to be diagnosed in about 2,500 people in the United States each year. The incidence is unknown, but one estimate places it at about 5-6 people per every 1,000,000 people in the general population.

Can melanoma have no pigment?

For example, certain melanomas may have no color at all. Physicians refer to these as “amelanotic” melanomas, because they are conspicuously missing melanin, the dark pigment that gives most moles and melanomas their color.

What does Desmoplastic mean?

Listen to pronunciation. (DES-moh-PLAS-tik) Causing or forming adhesions or fibrous connective tissue within a tumor.

Where does melanoma usually spread to first?

Normally, the first place a melanoma tumor metastasizes to is the lymph nodes, by literally draining melanoma cells into the lymphatic fluid, which carries the melanoma cells through the lymphatic channels to the nearest lymph node basin.

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What is the life expectancy of someone with melanoma?

The overall average 5-year survival rate for all patients with melanoma is 92%. This means 92 of every 100 people diagnosed with melanoma will be alive in 5 years. In the very early stages the 5-year survival rate is 99%. Once melanoma has spread to the lymph nodes the 5-year survival rate is 63%.

What is the most aggressive form of melanoma?

Nodular melanoma – This is the most aggressive form of cutaneous melanoma. It typically appears as a dark bump – usually black, but lesions may also appear in other colors including colorless skin tones. This type of melanoma may develop where a mole did not previously exist.