What kind of chemo is FOLFOX?

What type of treatment is FOLFOX?

An abbreviation for a combination chemotherapy regimen that is used to treat colorectal cancer. It includes the drugs leucovorin calcium (folinic acid), fluorouracil, and oxaliplatin. There are several different FOLFOX regimens, including FOLFOX-4, FOLFOX-6, modified FOLFOX-6 (mFOLFOX-6), and FOLFOX-7.

Is FOLFOX palliative chemotherapy?

Reduced dose intensity FOLFOX-4 as first line palliative chemotherapy in elderly patients with advanced colorectal cancer.

How bad is FOLFOX chemo?


Hair loss. Hand-foot syndrome (palmar-plantar erythrodysesthesia) redness, pain or peeling of palms and soles. Rash, increased risk of sunburn, itching. Diarrhea, nausea, vomiting, constipation, loss of appetite.

Is FOLFOX adjuvant chemotherapy?

Oxaliplatin-based chemotherapy (FOLFOX [folinic acid, fluorouracil, oxaliplatin] or XELOX [oxaliplatin, capecitabine; also called CAPOX]) for 6 months is the current standard for adjuvant therapy of stage III colon cancer patients with good performance status.

Can you lose hair with FOLFOX?

Hair loss is rare with this treatment, but you may notice hair thinning. If any of your hair does fall out, it will grow back after treatment has finished. What are the side effects of FOLFOX that I may have? Fatigue is the most common side effect reported by our patients.

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How successful is FOLFOX?

The researchers found that the 213 patients in the study had a 5-year overall survival rate of 77.9 percent. They found FOLFOX significantly increased the overall survival rate in patients who received at least eight cycles.

How many cycles of FOLFOX can you have?

You have FOLFOX chemotherapy as cycles of treatment each lasting 2 weeks. Depending on your needs, you may have up to 12 cycles.

Can you work while on FOLFOX?

The more treatments, the more likely you are to experience fatigue which can affect work. That said, most people are able to continue to work full time, perhaps with some time off for a day or two during or immediately after receiving a FOLFOX infusion.

Can FOLFOX cause heart problems?

The incidence of Takotsubo cardiomyopathy due to 5-fluorouracil based chemotherapeutic regimens like FOLFOX is not uncommon. It is also seen with platinum based chemotherapy. Most of these patients have reversible cardiotoxicity and the cardiac function recovers within a short period with supportive treatment.

Does FOLFOX shrink tumors?

FOLFOX chemo is given to shrink tumors and help decrease symptoms for a colon cancer patient. If the disease is not metastatic, it is commonly given with the goal of cure.

Can you drink alcohol on FOLFOX?

Avoid alcohol, cocaine and other recreational drugs which affect the liver. The liver is already under stress from processing the toxicities from the chemo. If you don’t eliminate alcohol entirely, it is advisable to at least limit alcohol consumption to only occasionally.

Does FOLFOX make you sick?

Nausea and vomiting are common with FOLFOX treatment. It is generally the worst for the first 12 to 48 hours after treatment. It often gets better in 3 to7 days.

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