What medications contain platinum?
- Approved platinum-based anticancer drugs.
Does chemo have platinum in it?
Platinum compounds, including cisplatin, carboplatin, and oxaliplatin, are some of the most commonly used and active chemotherapy drugs utilized by oncologists today.
What does platinum do in chemotherapy?
Platinum-based drugs are effective against cancer because at their centre is a platinum atom joined to two ammonion molecules and two chloride ions. The compound is negatively charged, but when it enters the cancer cell it becomes positively charged because the chloride ions are replaced by water molecules.
Which platinum complex is used in cancer chemotherapy?
The metal based compounds nowadays are used to treat cancer. Platinum complexes are used in treating cancer patients by its application in cancer chemotherapy treatment. Cisplatin is the first platinum complex which was observed to have anticancer activity.
What are the harmful effects of platinum?
* Platinum may cause a skin allergy. If allergy develops, very low future exposure can cause itching and a skin rash. * Platinum may cause an asthma-like allergy. Future exposure can cause asthma attacks with shortness of breath, wheezing, cough, and/or chest tightness.
What causes platinum resistance?
Resistance to platinum-containing drugs has been associated to several mechanisms, including alteration in drug efflux (through for example the modulation of the copper transporter CTR-1 expression) [1,2,3,4,5], alteration in intracellular proteins able to bind and sequester Pt (as for example GSH) [6,7,8,9], and …
What does platinum do to the body?
The health effects of platinum are strongly dependent upon the kind of bonds that are shaped and the exposure level and immunity of the person that is exposed. Finally, a danger of platinum is that it can cause potentiation of the toxicity of other dangerous chemicals in the human body, such as selenium.
Does platinum chemo cause hair loss?
Taste changes, metallic taste. Increases in blood tests measuring liver function. These return to normal once treatment is discontinued (see liver problems). Hair loss may cause hair loss; however, this side effect is uncommon.
Do platinum chemo drugs cause hair loss?
Why Chemo Causes Hair Loss
Chemotherapy drugs work systemically (throughout the body) by interfering with the division and growth of rapidly growing cells. The dose of chemotherapy: Higher doses generally have a greater risk for hair loss.
Is Taxol a platinum-based chemotherapy?
Usually, the combination includes a type of chemo drug called a platinum compound (usually cisplatin or carboplatin), and another type of chemo drug called a taxane, such as paclitaxel (Taxol®) or docetaxel (Taxotere®). These drugs are usually given as an IV (put into a vein) every 3 to 4 weeks.
What is platinum-based doublet chemotherapy?
Third generation platinum-based chemotherapy doublets, namely combinations of a platinum compound (cisplatin or carboplatin) with one third generation agent (mainly vinorelbine, gemcitabine or taxanes), represented the cornerstone of standard chemotherapy as first-line treatment of advanced NSCLC for almost a decade, …