Does folic acid increase breast cancer risk?
Folic acid is a well-known supplement to many women, particularly those who are or plan to be pregnant. But a new study suggests that taking large amounts of folate – a B vitamin – and its synthetic form, folic acid, might actually increase the risk of developing breast cancer.
Should cancer patients take folic acid?
Notwithstanding the lack of compelling supportive evidence, folic acid supplementation should be avoided in cancer patients and survivors and in highly predisposed and susceptible individuals at risk of developing cancer.
Why do cancer patients take folic acid?
Folic acid, also known as vitamin B9, is necessary for many metabolic systems. The dietary nutrient is required for cell division and replication. Folic acid supplementation is necessary to prevent severe toxicities when receiving certain chemotherapy drugs such as pemetrexed (Alimta).
Does folic acid affect estrogen?
Animal studies reported that folic acid, like estrogen, reduced noradrenaline secretion[59,60], and increased serotonin activity.
Does folic acid have side effects?
Most adults and children can take folic acid. If you’re pregnant or trying for a baby, it’s recommended you take folic acid until you’re 12 weeks pregnant. It helps your baby grow normally. You’re unlikely to get side effects with folic acid, but some people feel sick, lose their appetite, get wind or feel bloated.
Does folic acid help breast growth?
Large amounts of folic acid shown to promote growth of breast cancer in rats. Summary: Folic acid supplements at levels consumed by breast cancer patients and survivors in North America promoted the growth of existing breast cancer in rats, new research found.
What cancers cause low folic acid?
More recently, however, folate deficiency has been implicated in the development of cancer, notably of the cervix, lung, breast, brain and colorectum.
Does folic acid make cancer worse?
A large population study suggested an association between dietary folate intake and increased risk for overall skin cancer, basal cell carcinoma, and non-melanoma skin cancer, particularly in women (50). Over-consumption of folic acid supplements may also increase risk of toxicity and some cancers (51) (52).
Why folic acid is not good for cancer patients?
Folic acid and B12 supplementation was associated with a 21% increased risk for cancer, a 38% increased risk for dying from the disease, and an 18% increase in deaths from all causes. This finding was mainly driven by an increase in lung cancer incidence among the folic acid and B12-treated patients.
Does folic acid help clear HPV?
Our recent data demonstrated that women with higher folate status have the ability to clear HR-HPV infections, including HPV 16, and that HR-HPV positive women, especially HPV 16-positive women who have lower folate status, are significantly more likely to be diagnosed with CIN (OR=9, p <0.0001).
Can I take folic acid after breast cancer?
Folate supplements are sometimes recommended to reduce the small possible increased risk of breast cancer associated with alcohol use; however, research shows that taking folate supplements does not lower breast cancer risk. There is no evidence to support using folic acid to reduce depression.