Do cancer cells stop at checkpoints?
Recently, starting from the observation that cancer cells that have defective checkpoints, often because of p53 pathway mutations, can still stop the cell cycle and avoid DNA damage-induced cell death by relying on the other checkpoint branches , a novel anticancer therapeutic strategy has begun to develop.
What things can be malignant?
In a medical context, the word malignant is used to describe harmful masses or tumors that are cancerous and that grow and spread disease. The word benign is the opposite—it’s used to describe masses or tumors that are not cancerous (those that do not spread disease to other parts of the body).
Can a tumor grow overnight?
And they are deadly. In a surprise finding that was recently published in Nature Communications, Weizmann Institute of Science researchers showed that nighttime is the right time for cancer to grow and spread in the body.
When do random or spontaneous mutations happen?
Current research suggests most spontaneous mutations occur as errors in the repair process for damaged DNA. Neither the damage nor the errors in repair have been shown to be random in where they occur, how they occur, or when they occur.